I was working lately on project for connecting Sega Naomi IO Boards to a MAME PC just by Plug and Play. Normally a complete rewiring and Keyboard or Gamecontrol Encoder like Dual Strike
is needed for such a task.
The complete Control Panel of a Sega Naomi Cab is wirded to this IO Board. JVStrike grabs this
Sega Naomi output (a single USB Cable) and converts it to a HID Keyboard with MAME Standard Keyboard Layout.
Buttons and Sticks -> Sega Naomi IO Board -> JVStrike -> MAME PC
That's all, by just plugging two cables.
Step 1. Connect USB A Cable from Sega Naomi IO Board to JVStrike
Step 2. Connect USB B Cable to JVStrike to MAME PC
Step 3. Power on PC and IO Board